Candide by Voltaire Chapter 4 Page 7

Indians, the Persians, the Chinese, the Siamese, and the Japanese are entirely unacquainted with it; but there is a sufficing reason for them to know it in a few centuries. In the meantime, it is making prodigious havoc among us, especially in those armies composed of well disciplined hirelings, who determine the fate of nations; for we may safely affirm, that, when an army of thirty thousand men engages another equal in size, there are about twenty thousand infected with syphilis on each side.”

“Very surprising, indeed,” said Candide, “but you must get cured.”

“Lord help me, how can I?” said Pangloss. “My dear friend, I have not a penny in the world; and you know one cannot be bled or have an enema without money.”