On The Origin of Species by Charles Darwin Chapter 5 Page 7

variability, either directly or indirectly, but likewise to include natural selection, for the conditions determine whether this or that variety shall survive. But when man is the selecting agent, we clearly see that the two elements of change are distinct; variability is in some manner excited, but it is the will of man which accumulates the variations in certain direction; and it is this latter agency which answers to the survival of the fittest under nature.

2. Effects Of The Increased Use And Disuse Of Parts, As Controlled By Natural Selection

From the facts alluded to in the first chapter, I think there can be no doubt that use in our domestic animals has strengthened and enlarged certain parts, and disuse diminished them; and that such modifications are inherited.