On The Origin of Species by Charles Darwin Chapter 9 Page 22

We must, therefore, either give up the belief of the universal sterility of species when crossed; or we must look at this sterility in animals, not as an indelible characteristic, but as one capable of being removed by domestication.

Finally, considering all the ascertained facts on the intercrossing of plants and animals, it may be concluded that some degree of sterility, both in first crosses and in hybrids, is an extremely general result; but that it cannot, under our present state of knowledge, be considered as absolutely universal.

3. Laws Governing The Sterility Of First Crosses And Of Hybrids

We will now consider a little more in detail the laws governing the sterility of first crosses and of hybrids. Our chief object will be to see whether or